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Published March 20, 2007

Superfamily Assignments for the Yeast Proteome through Integration of Structure Prediction with the Gene Ontology
Lars Malmström, Michael Riffle, Charlie E. M. Strauss, Dylan Chivian, Trisha N. Davis, Richard Bonneau, David Baker
Protein three-dimensional structures were predicted for all Saccharomyces cerevisiae domains that were found to have no sequence similarity to any proteins of known structure.
Full-text | Author Summary | Screen PDF (592K)

Glucocorticoids Play a Key Role in Circadian Cell Cycle Rhythms
Thomas Dickmeis, Kajori Lahiri, Gabriela Nica, Daniela Vallone, Cristina Santoriello, Carl J. Neumann, Matthias Hammerschmidt, Nicholas S. Foulkes
To establish circadian cell cycle rhythms, cell-autonomous clock mechanisms act in concert with a systemic signaling environment of which glucocorticoids are an essential part.
Full-text | Author Summary | Screen PDF (518K)

H2A.Z-Mediated Localization of Genes at the Nuclear Periphery Confers Epigenetic Memory of Previous Transcriptional State
Donna Garvey Brickner, Ivelisse Cajigas, Yvonne Fondufe-Mittendorf, Sara Ahmed, Pei-Chih Lee, Jonathan Widom, Jason H. Brickner
Recruitment of active genes to the periphery of the yeast nucleus does not require concurrent transcription.
Full-text | Author Summary | Screen PDF (798K)

Independently Evolving Species in Asexual Bdelloid Rotifers
Diego Fontaneto, Elisabeth A. Herniou, Chiara Boschetti, Manuela Caprioli, Giulio Melone, Claudia Ricci, Timothy G. Barraclough
New analyses of genetic and morphological data reveal that the bdelloid rotifers, a famous asexual group, have diversified into distinct species and that sex is not a necessary condition for speciation.
Full-text | Author Summary | Screen PDF (742K)
Synopsis: Who Needs Sex (or Males) Anyway?

Protein Oxidation Implicated as the Primary Determinant of Bacterial Radioresistance
Michael J. Daly, Elena K. Gaidamakova, Vera Y. Matrosova, Alexander Vasilenko, Min Zhai, Richard D. Leapman, Barry Lai, Bruce Ravel, Shu-Mei W. Li, Kenneth M. Kemner, James K. Fredrickson
A high intracellular concentration of manganese in Deinococcus radiodurans protects proteins, but not DNA, from ionizing radiation-induced oxidative damage. Protein protection may be critical to the known radiation resistance of these bacteria.
Full-text | Author Summary | Screen PDF (1002K)
Synopsis: Paradox Resolved? The Strange Case of the Radiation-Resistant Bacteria

Fly Photoreceptors Demonstrate Energy-Information Trade-Offs in Neural Coding
Jeremy E. Niven, John C. Anderson, Simon B. Laughlin
Evidence from single-neuron recordings supports the law of diminishing returns, i.e., high performance eyes in larger, faster flies have less efficient photoreceptors than those of their small, sluggish counterparts.
Full-text | Author Summary | Screen PDF (705K)


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